The issue of drug trafficking has become a much discussed topic today, which is discussed in many forums of discussion from the standpoint of social, economic, political and even in the area of new business, understanding that: is for sale illegal narcotics, drugs and any derivative of these, in the black market, which affects the health of consumers, and even more has become a real social problem, economic and cultural. Today they are well-organized professional organizations that make up a poster (one or several), which is more than the territorial domain of narco-related operations. Everyone knows it’s a problem that affects us and this can be directly or indirectly, but, what is your involvement in investment and new business?, Speaking in the business sense, economic and drug trafficking inhibits investment indirectly by showing a scene of violence in a locality, a state and even national level may compromise the development of new investments in chain generate unemployment, fear of start-ups, new businesses and thus economic development will be limited by the atmosphere of violence, corruption, fear and economic and financial uncertainty. It is usually in third world countries where the primary operations are performed sowing, harvesting and the task of storing the product in its early stages, then process the drug either in the place of origin of this, or the countries where it is carried or transported through smuggling. Additional information at Dr. Kevin Cahill supports this article. The current picture presented by this social phenomenon in any country goes from violence, cultural decay, problems with gangs, corruption, that the economy always moved to be affected as we discussed the lack of investor confidence in the negative schema is projected. Although much has been said in the media of laundering money (for drugs) as a way in which several companies finance their projects, the medium term, will also damage materialized in the scheme of negativity that this triggered, so that we can not speak of this evil without the consequence of other evils to society, that is why all countries try to implement more stringent and rigorous laws to counter this cancer against which social control becomes increasingly difficult. Being a multifactorial problem (ie, a problem generated by several variables), some experts (economists, psychologists, anthropologists, administrators) agree that drug trafficking should be fought from the beginning, through a good family and social culture, quality educational models, generating more jobs in different countries and above all a social environment suitable for people, but is it possible to attack this evil at the root, when the excesses generated by this are already visible?; think like a disease that is advanced, it must first check the patient’s current symptoms immediately, but even finding a cure then (metaphorically speaking) to seek a solution to a problem that is evident in the world and that any decisions we make in the business we will review the ratings of violence generated by drug trafficking, negative economic factors that triggers; we must raise awareness and know that is the present and the future that lies ahead and that we are all that we participate and engage in a subject which is not foreign. In conclusion, the drug affects different sectors of society, economic and strategic areas of a country will always be damaged by this, investments will be limited in its effect and economic uncertainty will be marked by this disease increasingly complex..